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外周麻醉对患有先兆子的患者视神经外直径的影响:一项前性观察性研究
Sun-Kyung Park1, Hansol Kim2, Youngwon Kim1
1Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Regional anesthesia and pain medicine
|July 1, 2024
概括
周周麻醉在预先患者中没有增加视神经外直径 (ONSD),尽管他们的基线ONSD较高. 这表明,外周麻醉对于患有脑内压力增加风险的孕前患者来说是安全的.
科学领域:
- 麻醉学 麻醉学
- 产科 产科 产科 产科 产科
- 神经学 神经学
背景情况:
- 视神经外直径 (ONSD) 是脑内压力的指标,在子宫前经常升高.
- 外周麻醉涉及注射大量的溶液,可能会影响ONSD.
- 这项研究研究了外周局部麻醉剂注射对在子宫前时的ONSD的影响.
研究的目的:
- 为了确定外周麻醉的施用是否会增加患有先兆子的患者的ONSD.
- 为了比较孕妇在经外注后ONSD的变化,在预扣留和正常血压的孕妇之间进行了外注.
主要方法:
- 一项比较性研究,涉及11名经过剖腹产分娩的11名前性和11名正常血压的孕妇.
- 用2%的利多卡因和50微克芬太尼进行了外周麻醉.
- 在外周注射前和后对ONSD进行序列测量,并使用线性混合模型进行分析.
主要成果:
- 与正常血压女性相比,患有先兆子的患者的ONSD基线显著更大 (5.7毫米vs4.1毫米).
- 在任何一组中,注射后3分钟ONSD与基线没有显著变化.
- 连续分析证实,在两个组内外麻醉后,ONSD没有显著变化.
结论:
- 外周麻醉在孕前患者中不会进一步提高ONSD.
- 研究结果支持在孕前患者中安全使用外周麻醉,即使内压升高,假设没有其他内病理.
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