生活必需品8与高灵敏度C反应蛋白相反相关
Lana Hebib1, Ángel Herraiz-Adillo2, Sara Higueras-Fresnillo2,3
1Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden. lana.hebib@liu.se.
Scientific reports
|July 1, 2024
概括
通过生活必需品8 (LE8) 改善心血管健康,显著减少炎症. 较高的LE8分数与较低的高灵敏度C反应蛋白 (hs-CRP) 相关,表明整体健康状况更好.
科学领域:
- 心血管健康 心血管健康
- 炎症生物标志物 炎症生物标志物
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 的发展与炎症有关.
- 生命的基本8 (LE8) 测量了8个关键的心血管健康指标.
- LE8包括饮食,体育活动,尼古丁暴露,睡眠,胆固醇,葡萄糖,血压和BMI.
研究的目的:
- 为了研究心血管健康之间的关联,以LE8测量,和低级炎症.
- 分析LE8得分与高灵敏性C反应蛋白 (hs-CRP) 水平之间的关系.
主要方法:
- 基于人口的横截面研究 (SCAPIS) 涉及28010名参与者 (年龄在50-64岁之间).
- 基于8个组成部分计算的LE8分数 (0-100分).
- 用于评估LE8分数与高hs-CRP (>3.0 mg/L) 之间的关联的后勤回归和线条分析.
主要成果:
- 在LE8得分和hs-CRP水平之间发现了强烈的剂量反应反向关联.
- 与LE8得分低 (≤50.0) 的参与者相比,与LE8得分高 (≥80.0) 的参与者相比,高hs-CRP的几率是5.8倍.
结论:
- 更加坚持"生活必需8项"指导方针,与较低的炎症水平有很强的联系.
- 改善心血管健康指标可能是减少全身炎症的策略.
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