腰椎椎间盘的患者中单层次和多层次椎间盘退化之间的准脊柱肌肉脂肪透的差异
Minjie Shen1, Zhijia Shen1,2, Guanyu Yang1,2
1Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, China.
Orthopaedic surgery
|July 2, 2024
概括
腰椎间盘 (LDH) 和多层次椎间盘退化 (IDD) 患者在多 (MF) 和直立脊柱 (ES) 肌肉中表现出更严重的脂肪透. 这种肌肉脂肪透是LDH患者多级IDD的独立风险因素.
科学领域:
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
- 脊柱外科手术 脊柱外科手术
背景情况:
- 在腰椎间盘 (LDH) 患者中,多个水平的椎间盘退化 (IDD) 与不良结果相关.
- 疑似与IDD相关的是副脊柱肌肉的脂肪透,但关于单级和多级IDD的具体数据有限.
研究的目的:
- 为了在LDH患者中比较单级和多级IDD之间的副脊髓肌肉脂肪透程度.
- 确定副脊髓肌肉脂肪透是否是LDH患者多级IDD的独立风险因素.
主要方法:
- 对82名LDH患者 (27个单级IDD,55个多级IDD) 的回顾性分析.
- 计算机断层扫描 (CT) 测量了多体 (MF),直立脊柱 (ES) 和心肌 (PM) 的密度值.
- 后勤回归分析用于识别多层次IDD的独立风险因素,调整年龄,性别和BMI等混因素.
主要成果:
- 与单一级IDD患者相比,多级IDD患者年龄大得多,在MF,ES和PM中脂肪透水平较高 (CT密度较低).
- 脂肪透MF和ES与多级IDD有显著的关联,即使经过对混因素进行调整.
- 体重指数 (BMI) 并没有显著改变肌肉脂肪透和多级IDD之间的关联.
结论:
- 与单级IDD患者相比,患有多级IDD的患者在多肌 (MF) 和直立脊柱 (ES) 肌肉中表现出更明显的脂肪透.
- 脂肪透于MF和ES肌肉被确定为LDH患者多级IDD发展的独立风险因素.
相关概念视频
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...

