禁食血糖作为在第三个三个月的晚期发病妊娠糖尿病查措施
Xiaoxia Tang1,2, Jin Wei2, Shaohua Wu2
1Shanghai General Hospital of Nanjing Medical University, Shanghai, China.
晚期妊娠糖尿病 (GDM) 影响6.3%的怀孕正常初始查. 这种情况显著增加了宏观症和NICU转移的风险,即使在标准治疗后.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 孕期糖尿病查通常发生在怀孕早期.
- 晚期发病的GDM,在第二个三个月后被诊断出来,需要进一步的研究.
- 标准GDM查可能会错过怀孕后期发展的病例.
研究的目的:
- 在32-34周使用额外的空腹血糖 (FBG) 查来确定晚发性GDM的患病率.
- 在被诊断为晚发性GDM的怀孕中分析围产期结局.
- 评估晚发性GDM标准治疗的有效性.
主要方法:
- 一项前性队列研究,涉及1130个单独怀孕.
- 在妊娠32-34周之间进行了额外的FBG查.
- 怀孕时FBG≥5.1 mmol/L被诊断为GDM,并接受标准化治疗;结果进行了比较.
主要成果:
- 晚发性GDM在6.3%的参与者中被诊断出来.
- 晚期发病的GDM组显示了显著更高的宏观症 (22.7%对5.1%) 和NICU转移 (18.3%对10.1%) 的比例.
- 增加的FBG与母亲超重或肥胖相关 (54.9%对34.9%).
结论:
- 在32-34周的额外FBG查中,在6.3%的怀孕中,在最初正常查的情况下,可以识别晚发性GDM.
- 晚期发病的GDM与宏观症和NICU入院的风险增加有关,在标准治疗后持续存在.
- 针对晚发性GDM进行有针对性的查对于改善围产期结果至关重要.
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