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Updated: Jun 22, 2025

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery
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Published on: May 30, 2025

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表观遗传药物对CRISPR-Cas9编辑的染色体上下文依赖的影响

Ruben Schep1,2, Max Trauernicht1,2, Xabier Vergara1,2,3

  • 1Oncode Institute, The Netherlands.

Nucleic acids research
|July 2, 2024
PubMed
概括

表观遗传药物可以改变CRISPR-Cas9基因编辑效率和结果. 这项研究表明药物效应因染色体位置而异,为向CRISPR改进提供了资源.

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