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Updated: Jun 22, 2025

An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity
12:02

An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity

Published on: November 2, 2016

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尿素功能化的氨基甲基胺衍生物作为抗莱什曼病剂

Muhammad Sajid1, Hina Siddiqui1,2, Humaira Zafar3

  • 1H.E.J. Research Institute of Chemistry, International Center for Chemical & Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.

Future medicinal chemistry
|July 2, 2024
PubMed
概括

研究人员合成了23种氨酸衍生物,以发现新的抗莱什曼病剂. 化合物7v对Leishmania major和Leishmania tropica表现出强烈的活性,没有毒性,将其确定为有前途的候选药物.

关键词:
(±) - 氨基甲基化物皮肤上的莱什曼病.细胞毒性 细胞毒性这种类型的氨酸.

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