外腔室排水的管理:断奶还是不断奶?
Tim Jonas Hallenberger1,2, Thavena Tharmagulasingam2, Maria Licci1
1Department of Neurosurgery, University Hospital of Basel, Spitalstrasse 21, 4031, Basel, Switzerland.
Acta neurochirurgica
|July 2, 2024
概括
逐渐的外部心室排水 (EVD) 断奶并没有降低永久性脑脊液转移率. 然而,与快速关闭相比,这种策略增加了感染风险和住院时间. 直接EVD关闭可能是最好的.
科学领域:
- 神经外科 神经外科
- 关键护理医学 关键护理医学
- 神经外科手术 神经外科手术
背景情况:
- 外腔室排水 (EVDs) 在神经外科手术中很常见,15-30%的患者需要永久的脑脊液 (CSF) 转移.
- 断奶EVD的最佳策略仍然不确定,关于逐步或快速关闭方法的持续辩论.
研究的目的:
- 为了比较逐渐EVD断奶和快速关闭之间的永久CSF转移率.
- 评估二次结果,包括住院时间和与埃博拉病毒相关的发病率.
主要方法:
- 从2010年到2020年进行了一项单一中心的回顾性队列研究.
- 患者被分为一个逐渐断奶组 (WG) 和一个非断奶 (快速关闭) 组 (NWG).
- 主要结果是永久性CSF转移率;次要结果包括住院时间和感染率.
主要成果:
- 在断奶组 (39.9%) 和未断奶组 (37.8%) 之间,永久性CSF转移率相似.
- 断奶组的EVD相关感染率 (13.5%对1.8%) 和非EVD相关感染率 (2.8%对0%) 显着更高.
- 与未断奶组 (23.66天) 相比,断奶组的住院时间更长 (24.93天).
结论:
- 逐渐的EVD断奶似乎不会减少永久CSF转移的必要性.
- 逐渐断奶与感染率增加和住院时间延长有关.
- 应考虑直接封闭EVD作为临床选择.
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