风险老年人识别 (ISAR) 评分和可能不适当的处方:一个回顾性队列研究
Julien Bamps1, Sophie Lelubre2, Anne-Sophie Cauchies3
1Clinical Pharmacy Unit, Faculty of Medicine and Pharmacy, University of Mons (UMONS), Chemin du Champ de Mars, 25, Bât. 6, 7000, Mons, Belgium. julien.bamps@umons.ac.be.
风险老年人识别 (ISAR) 评分和药物数量是老年人潜在不适当处方 (PIP) 的关键因素. 这些指标可以帮助患者优先考虑处方审查,以改善健康结果.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 健康 结果 研究 研究 结果
背景情况:
- 在老年人中,潜在的不适当处方 (PIP) 会增加不良健康风险.
- 目前的方法缺乏明确的策略来优先考虑患者的处方审查.
- 识别有风险的老年人对于药物安全至关重要.
研究的目的:
- 评估"处于风险中的老年人识别" (ISAR) 评分与PIP发病率之间的关联.
- 确定ISAR得分是否可以预测潜在不合适药物 (PIM) 和潜在的处方遗漏 (PPO) 的数量.
主要方法:
- 一项为期12个月的回顾性医院研究分析了266名患者的病历.
- 使用STOPP/START工具识别了可能不合适的处方 (PIP).
- 多变量线性回归和ROC曲线分析评估了ISAR得分的预测能力.
主要成果:
- 观察到PIP的高患病率:PIM为80.1%,PPO为54.9%.
- ISAR评分和药物的数量是PIP的重要决定因素.
- 药物的数量预测了PIM,而养老院住所预测了PPO.
结论:
- 在老年人中,ISAR评分和药物计数是PIP的独立预测因素.
- 整合ISAR评分和药物计数可以优化处方审查的患者优先级.
- 这种方法支持有针对性的干预措施,以提高药物适当性和患者安全.
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