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Updated: Jun 22, 2025

A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM
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通过设计优化贝达基林固体脂质纳米颗粒的质量方法,以提高产品性能

Mercy A Okezue1,2, Chidi Uche3, Adekoya Adebola4

  • 1Industrial and Molecular Pharmaceutics Department, Purdue University, West Lafayette, Indiana, 47907, USA. Amaka_u@hotmail.com.

AAPS PharmSciTech
|July 2, 2024
PubMed
概括

这项研究开发了口服贝达基林固体脂质纳米颗粒 (SLN),以改善结核病治疗的坚持. 口服SLN配方改善了药物输送和患者的服药效果,相比于亲肠道选择.

关键词:
美国能源部解散率 解散率 解散率 解散率增强的可溶性 增强的可溶性脂质纳米颗粒 (s)优化的优化优化优化.颗粒大小 颗粒大小从设计开始的质量.

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