基本和有毒元素的血混合物的暴露与住院老年人的脂质概况之间的关联
Daniela Antunes Pacheco1, Angélica Lopes de Sousa Campêlo1, Sara Estéfani Soares de Sousa2
1Graduate Program in Nutrition, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, 3000 - Lagoa Nova, Natal, RN CEP: 59078900, Brazil.
概括
老年人的基本和有毒元素水平较低.
科学领域:
- 环境健康 环境健康
- 老年学是指老年学的学科.
- 生物化学 生物化学
背景情况:
- 年长的成年人表现出降低排毒能力,易患脂质障碍和改变血糖控制.
- 在这个人口群体中,研究血化学元素与代谢健康之间的联系至关重要.
研究的目的:
- 评估了老年人医院住院的血和脂质/血糖特征中的必需和有毒元素混合物之间的关联.
- 确定影响这些代谢参数的特定因素.
主要方法:
- 在149名巴西老年人 (≥60岁) 中分析了16种化学元素的血度,脂质概况和血糖控制.
- 采用贝叶斯核机器回归来建模元素混合物与代谢变量 (总胆固醇,HDL-c,LDL-c,甘油三,葡萄糖,HbA1c) 之间的关联.
主要成果:
- 在铁 (Fe) 和总胆固醇 (TC),LDL-c和甘油三 (TG) 之间发现了非线性关系.
- (Ba) 和铜 (Cu) 显示与TG的非线性关联.
- 整体元素混合物的较低度 (低于第35百分位数) 与TC的降低相关,Fe是主要的贡献者.
结论:
- 基本和有毒元素的血度降低显示出对老年人TC升高的保护作用,铁起着关键作用.
- 建议对老年人血元素水平进行常规查,以预防失脂症并指导临床管理.
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