相关实验视频

Updated: Jun 22, 2025

Microfluidics in Assessing Platelet Function

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

神奇的数字63 - 重新定义老年人年龄在创伤中进行大规模输血

Joseph C L'Huillier¹, Heather J Logghe², Shuangcheng Hua³

¹Department of Surgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York; Division of Health Services Policy and Practice, Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York; Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Erie County Medical Center, Buffalo, New York.

The Journal of surgical research

|July 2, 2024

概括

65岁的标准老年人年龄对于大规模输血 (MT) 风险是不准确的. 一个新的63岁的门确定了在MT后死亡率较高和结果更差的患者,无论伤害严重程度如何.

科学领域:

创伤外科手术创伤外科
关键护理医学关键护理医学
老年医学老年医学

背景情况:

传统的65岁老年年龄截止值可能无法准确地识别大量输血 (MT) 后死亡风险增加的老年人.
需要重新定义MT的老年年龄门,以更好地了解其与患者结果的关联.

研究的目的:

重新定义大量输血 (MT) 的老年年龄门.
调查重新定义的老年人年龄与MT后的结果之间的关联.

主要方法:

使用了2013-2018年创伤质量改善计划数据库,用于在24小时内接受≥10单位包装红细胞 (pRBC) 的成年人.
采用启动式分析和后勤回归来确定不同年龄段的输血徒劳门 (TTs).
确定了老年和年轻人群体的TT变得具有统计意义的年龄,以定义MT的新"老年"年龄.

主要成果:

输血无用度值 (TT) 的差异在63岁的年龄截止时变得显著.
年龄≥63岁的患者 (新老年人群) 的pRBC的TT为34个单位,而年龄<63岁的患者的TT为40个单位 (P=0.04).
尽管伤害不那么严重,但新老年人群 (n=2870) 的整体死亡率较高 (62%对45%,P<0.01) 和出院率较低 (7%对35%,P<0.01).

结论:

大规模输血 (MT) 的最佳老年年龄门是63岁,输血无用度门 (TT) 为34个单位.
通过这一新值识别的生理上"老年"患者在MT后经历了更糟糕的结果,包括死亡率增加和家庭出院减少.
这项研究挑战了任意的65年截止值,并提出了更准确的定义,用于识别创伤复苏中的高风险老年人.

关键词:

年龄年龄年龄年龄年龄年龄输血输血输血输血输血输血输血老年人医院老年人医院在TQIP,TQIP.输血门是指输血的门值.创伤是一个创伤.

更多相关视频

Integrated Compensatory Responses in a Human Model of Hemorrhage

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

相关概念视频

Blood Transfusion and Agglutination

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

Blood Transfusion

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...