在SARS-CoV-2和RSV支气管炎的结局中.
Donna R Mendez1, Krishna Paul1, Joan Richardson2
1University of Texas Medical Branch: Galveston - Department of Emergency Medicine, 301 University Blvd, Galveston, TX 77555-1173, United States.
Heart & lung : the journal of critical care
|July 2, 2024
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 支气管炎与呼吸道同胞性病毒 (RSV) 相比,与更高的ICU入院风险有关. 在第二次延迟的RSV季节,SARS-CoV-2支气管炎的结果更为严重.
科学领域:
- 病毒学 病毒学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 由于COVID-19大流行引入了严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 支气管炎,这种疾病的现有文献有限.
- 了解SARS-CoV-2支气管炎对于在疫情期间管理呼吸道感染至关重要.
研究的目的:
- 为了比较由SARS-CoV-2引起的支气管炎的临床结果与呼吸道同胞性病毒 (RSV).
- 在大流行期间对两个中断的RSV季节的结果进行子组分析.
主要方法:
- 使用美国TrinetX数据库从2020年3月1日到2023年1月1日进行的回顾性研究.
- 雇员倾向与对照对照,以使患者群之间的混变量相匹配.
主要成果:
- 在倾向匹配3592名患者 (每组为1796人) 后,SARS-CoV-2支气管炎显示氧和率≤95%和ICU入院的风险增加.
- 然而,与RSV相比,SARS-CoV-2支气管炎降低了住院的风险,呼吸率≥60或≥70.
- 在第二次延迟的RSV季节,RSV支气管炎患者的ICU入院风险低于SARS-CoV-2患者.
结论:
- 患有SARS-CoV-2支气管炎的患者经历了更严重的结果,其证据是ICU入院的风险更高.
- 在第二次延迟的RSV季节中,SARS-CoV-2支气管炎的严重性比RSV支气管炎更大.
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