屠宰过程对猪尸体的微生物群落和抗菌素耐药性基因产生影响
Tara N Gaire1, Carissa Odland2, Bingzhou Zhang3
1Department of Veterinary Population Medicine (VPM), College of Veterinary Medicine, University of Minnesota, Saint Paul, MN, USA.
The Science of the total environment
|July 2, 2024
概括
屠宰场的干预措施显著减少了猪肉尸体上的抗菌素耐药性基因 (ARG) 和微生物,无论农场的抗菌素暴露程度如何. 加工降低了ARG数量,但增加了金属和生物抗药性基因的相对丰富性.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 食品安全 食品安全
背景情况:
- 屠宰过程对肉类的微生物群落和抗菌素耐药性基因 (ARG) 有影响.
- 了解这些影响对于食品安全和公共卫生至关重要.
研究的目的:
- 研究屠宰场的过程如何影响猪的抗体微生物组.
- 评估农场对抗微生物药物暴露对这些变化的影响.
主要方法:
- 使用有针对性的丰富元基因组学来识别ARG.
- 在加工过程中,从猪皮和猪体上顺序采集了抽样.
- 在屠宰前,屠宰期间和屠宰后分析了耐药性和微生物特征.
主要成果:
- 在屠宰前和屠宰后观察到耐药性和微生物特征的显著变化.
- 屠宰场干预导致ARG数量,多样性和微生物DNA负载的下降.
- 发现了抗基因相对丰富的增加,主要是在Pseudomonadaceae和Enterobacteriaceae中.
结论:
- 屠宰场的干预措施有效地减少了猪肉尸体上的总体细菌负担,包括ARG.
- 屠宰和加工塑造了尸体的微生物和ARG特征.
- 该研究强调了屠宰场在管理抗微生物药物耐药性传播中的作用.
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