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相关概念视频

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Allergic Reactions02:06

Allergic Reactions

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Overview
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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相关实验视频

Updated: Jun 22, 2025

Basophil Activation Test for Allergy Diagnosis
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Basophil Activation Test for Allergy Diagnosis

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在喘中使用过敏原免疫疗法.

Kazuyuki Nakagome1, Makoto Nagata1

  • 1Department of Respiratory Medicine and Allergy Center, Saitama Medical University, Saitama, Japan.

Allergology international : official journal of the Japanese Society of Allergology
|July 2, 2024
PubMed
概括

过敏原免疫疗法 (AIT),包括皮下 (SCIT) 和舌下 (SLIT) 方法,为喘和过敏性鼻炎等过敏性疾病提供长期益处. 这种治疗可以改善症状,减少药物需求,并可能预防新的敏感性.

科学领域:

  • 免疫学 免疫学 免疫学
  • 过敏学 过敏学
  • 呼吸系统医学 呼吸系统医学

背景情况:

  • 过敏性疾病,包括喘和过敏性鼻炎,影响着相当一部分人口.
  • 目前的治疗方法往往可以控制症状,但不能改变疾病的进程.
  • 过敏原免疫疗法 (AIT) 是一种改变疾病的治疗选择.

研究的目的:

  • 审查过敏原免疫疗法 (AIT) 对过敏性疾病,特别是喘和过敏性鼻炎的疗效和长期影响.
  • 探索AIT的潜力,以改变过敏性疾病的自然过程,并防止新的敏感化.
  • 调查AIT超出目标过敏原的更广泛的免疫调节作用.

主要方法:

  • 对过敏性疾病的皮下免疫疗法 (SCIT) 和舌下免疫疗法 (SLIT) 现有文献的综述.
  • 对研究的分析,重点是针对喘和过敏性鼻炎的室内灰尘 (HDM) 特定的AIT.
  • 检查有关AIT效应的长期维持及其对疾病进展的影响的数据.

主要成果:

  • HDM-SCIT改善了喘症状,呼吸道过敏反应 (AHR),并减少了正常肺功能患者的药物需求.
  • 包括HDM-SLIT在内的AIT可以减轻喘恶化并改善同时存在过敏性鼻炎的患者的肺功能.
关键词:
过敏原免疫疗法免疫疗法过敏性鼻炎是一种过敏性鼻炎.支气管喘 支气管喘是一种皮下免疫疗法是一种皮下免疫疗法.语言下免疫疗法 语言下免疫疗法

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  • 过敏性鼻炎的效应在治疗后持续数年,可以预防过敏性鼻炎患者的喘发作,并可以抑制新的过敏原敏感化.

    • 结论:

    • 过敏原免疫疗法是对过敏性喘和过敏性鼻炎的有效治疗方法,提供持续的益处.
    • 艾滋病毒证明了疾病修饰的潜力,包括预防疾病的进展和新的敏感性.
    • 新出现的证据表明,AIT可能具有更广泛的免疫调节作用,可能抑制非向反应并增强对呼吸道感染的抵抗力.