血液透析诱导的板状晶状体的位置变化
Ji Hong Kim1,2, Hyo Chan Jeong1,2, Yong Un Shin1,3
1Department of Ophthalmology, Hanyang University College of Medicine, 222-1, Wangsimni-ro Seongdong-gu, Seoul, 104763, Korea.
Scientific reports
|July 2, 2024
概括
血液透析 (HD) 在末期脏疾病 (ESKD) 患者中显著降低了前面膜深度 (LCD). 这一发现表明,血液透析会影响视神经头部,特别是眼膜.
科学领域:
- 眼科医生 眼科 眼科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 医疗成像医学成像
背景情况:
- 末期病 (ESKD) 影响多个器官系统.
- 视神经头部 (ONH) 的健康对视力至关重要.
- 血液透析 (HD) 是对ESKD的维持生命的治疗方法.
研究的目的:
- 为了研究血液透析对视神经头部的晶片膜 (LC) 的作用.
- 通过扫描源光学连贯断层扫描 (SS-OCT) 来评估ONH参数的变化.
- 为了将LC深度的变化与眼睛和系统参数相关联.
主要方法:
- 对29名患有HD的ESKD患者进行前性观察性研究.
- 用于测量ONH参数的SS-OCT:神经通道直径 (NCD),周周垂直高度 (PVH) 和前侧LC深度 (LCD).
- 在HD之前和之后对ONH参数进行统计分析,并进行相关性分析.
主要成果:
- 在HD后的前部液晶显示屏的平均值显著下降,从441.6 ± 139.8μm降至413.5 ± 141.7μm (P=0.001).
- 没有观察到HD后NCD和PVH的显著变化 (分别P=0.841和P=0.574).
- 在前部液晶显示器和平均眼球 perfusion 压力 (r=0.397,P=0.036) 的变化之间发现了显著的相关性.
结论:
- 血液透析导致前面膜深度的显著减少.
- 这些发现表明,HD可以影响视神经头部结构,特别是LC.
- 需要进一步的研究来了解这些变化的长期影响.
相关概念视频
Glaucoma: Overview
538
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
538
Open Angle Glaucoma: Treatment
427
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
427
Renal Corpuscle
1.9K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
1.9K
Angle Closure Glaucoma: Treatment
471
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
471
Dialysis
288
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
288


