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Updated: Jun 22, 2025

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通过准miR-497-5p/SPP1轴,LncRNA TRPM2-AS促进子宫内膜癌的进展和血管生成

Hanbo Ma1,2,3, Fengyun Weng4, Xiaowen Tong3

  • 1Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, China.

Cellular & molecular biology letters
|July 3, 2024
PubMed
概括

长非编码RNATRPM2-AS通过海绵miR-497-5p增加SPP1.1,促进内皮癌 (EC) 的生长和血管生成. 削弱TRPM2-AS抑制了EC致癌性,提供了一个新的治疗点.

关键词:
血管新生的产生.宫内膜癌 (Endometrial carcinoma) 是一种子宫内膜癌.在LncRNA TRPM2-AS中.在 MiR-497-5p 里面.SPP1 SPP1 这是一个很好的选择.

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