系统性硬化症中的肺动脉高血压:全国性住院分析
Hania Sami1, Faria Sami2, Almurtada Razok2
1Shalamar Medical and Dental College.
ARP rheumatology
|July 3, 2024
概括
系统性硬化症 (SSc) 中的肺动脉高血压 (PAH) 与更糟糕的健康结果和增加的医疗保健成本有关. 在SSc患者中,PAH的早期诊断和管理至关重要.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
背景情况:
- 系统性硬化症 (SSc) 是一种复杂的自身免疫性疾病,具有显著的发病率.
- 肺动脉高血压 (PAH) 是SSc的严重并发症,影响预后.
- 了解SSc-PAH的流行病学和影响对于患者护理至关重要.
研究的目的:
- 确定SSc患者中PAH的流行率和流行病学.
- 评估PAH对美国SSc住院的影响.
- 分析与SSc-PAH相关的死亡率,发病率和医疗负担.
主要方法:
- 使用了2016-2019年国家住院样本 (NIS) 数据库.
- 分析了SSc和同时存在的PAH (SSc-PAH) 的成人住院病例.
- 使用统计回归检查了流行病学变量,死亡率,次要结果和医疗保健成本.
主要成果:
- 16.89%的SSc住院患者有同时存在的PAH.
- 对于SSc-PAH患者,死亡率更高,住院时间更长,医院总费用增加.
- 在SSc-PAH中观察到心力衰竭,呼吸机使用,心脏骤停,功能衰竭和血栓栓塞事件的显著增加.
结论:
- 在SSc中,PAH与明显更糟糕的结果有关,包括较高的死亡率和发病率.
- 与没有PAH的SSc相比,SSc-PAH给医疗保健带来了更大的负担.
- 这种PAH不成比例地影响白人,非裔美国人和亚洲人群,强调了有针对性的查和管理策略的必要性.
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