在内镜正常食道胃管腺镜检查中获得的肠道活检的评估:一项回顾性队列研究
Burak Dinçer1, Sinan Ömeroğlu, Onur Güven
1Department of General Surgery, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkiye.
在食管胃管腺镜检查 (EGD) 期间进行例行活检采样,发现正常的结果可以揭示显著的组织病理状况,如H. pylori和肠道代谢,有助于诊断.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 内镜检查是指内镜检查.
背景情况:
- 在正常内镜检查结果的食管胃管腺镜术 (EGD) 期间进行例行活检的必要性仍在争论中.
- 这项研究追溯分析了经过活检采样的EGD发现正常的患者.
研究的目的:
- 评估EGD期间内镜检测结果正常的患者活检采样的诊断产量.
- 为了确定这个患者群体中组织病理异常的患病率.
主要方法:
- 一个单一中心的回顾性队列研究,涉及2021年至2023年期间接受EGD的671名患者.
- 所有患者呈现出正常的内镜检测结果,并接受了活检采样.
- 收集的数据包括人口统计和临床病理学发现;研究登记在临床试验.gov (NCT06269380).
主要成果:
- 在38.7%的患者中发现了异常的组织病理学发现.
- 在29.8%的患者中检测到Helicobacter pylori阳性.
- 在有异常发现的患者中,发现了30.8%的肠道代谢 (IM),在老年患者和轻度胃炎患者中更为频繁. 胃炎的严重程度与H. pylori的存在和密度相关.
结论:
- 在EGD中采用正常内镜检测结果的活检样本可以显著促进诊断和治疗规划.
- 常规活检对于检测诸如H. pylori和IM之类的隐性病理非常有价值.
- 组织病理学分析提供了超越视觉内镜评估的关键信息.
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