对于炎症性肠道疾病的饮食疗法的革命
Sarah L Melton1,2, Alice S Day3,4,5, Robert V Bryant3,4,5
1Department of Gastroenterology Monash University & Alfred Health Melbourne Victoria Australia.
概括
饮食干预正在彻底改变炎症性肠病 (IBD) 治疗. 虽然排他性肠道营养对克罗恩病诱导有希望,但对于性结肠炎和长期维持疗法需要更多的研究.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- 饮食日益被认为是影响炎症性肠病 (IBD) 易感性和进展的重要环境因素.
- 治疗IBD的饮食方法历来缺乏强有力的证据,但现在正在获得引力.
- 新兴研究强调了饮食作为管理IBD的可修改因素的潜力.
研究的目的:
- 审查有关IBD诱导和维持饮食疗法的现有证据.
- 评估针对克罗恩病和性结肠炎的特定饮食的疗效.
- 识别IBD营养方面的知识缺口和未来研究领域.
主要方法:
- 对IBD饮食干预措施的现有文献进行系统审查.
- 对专注于排他性肠道营养和克罗恩病排除饮食用于诱导疗法的研究进行分析.
- 检查有关克罗恩病和性结肠炎的饮食维持策略的数据.
主要成果:
- 排他性肠道营养和克罗恩病排除饮食对克罗恩病诱导有希望,但长期来看是不可持续的.
- 对于克罗恩病的饮食维护疗法的证据在食品成分强化或抑制方面存在矛盾.
- 对于性结肠炎,植物性,高纤维,低动物蛋白饮食表明潜在的益处,尽管数据不那么强大.
结论:
- 饮食疗法正在成为IBD管理的重要工具,特别是在克罗恩病的诱导方面.
- 需要进一步进行高质量的研究,以确定克罗恩病和性结肠炎的最终饮食建议.
- 由于缺乏具体证据,基于人口的健康饮食指南仍然是IBD患者的默认建议.
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