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Updated: Jun 22, 2025

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
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使用分子动力学模拟分析蛋白质骨干NH和侧链甲基组的动力学分析

Nooriel E Banayan1, Andrew Hsu2, John F Hunt1

  • 1Department of Biological Sciences, Columbia University, 3000 Broadway, New York, New York 10027, United States.

Journal of chemical theory and computation
|July 3, 2024
PubMed
概括

分子动力学模拟和NMR实验揭示了蛋白质动力学. 优化的模拟准确地预测了Escherichia coli核糖核酶HI的一般化顺序参数,提高了我们对酶灵活性的理解.

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