在Endourologic程序中遵守抗菌预防指南:频率和相关结果
Sondos Abdaljaleel1, Mariam Abdeljalil1, Oriana Awwad1
1Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, Jordan.
Surgical infections
|July 3, 2024
概括
手术抗微生物预防 (SAP) 在内分泌手术中的坚持是不理想的,在抗生素持续时间上有显著的偏差. 优化SAP对于减少感染并发症,如尿路感染和血液感染至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术抗微生物预防 (SAP) 对于在内分泌手术后预防感染至关重要.
- 基于证据的指导方针存在,以优化SAP,但遵守情况各不相同.
- 传染性并发症,包括尿路感染 (UTI) 和血液感染 (BSI),可能会影响患者的结果.
研究的目的:
- 评估在内分泌外科手术中对SAP的国际指南的遵守情况.
- 通过这些程序来确定UTI和BSI的比率.
- 确定当前SAP实践中需要改进的领域.
主要方法:
- 一项前性横截面研究,涉及361名接受内分泌手术的患者.
- 对医疗记录的审查,以遵守有关抗生素指示,持续时间,选择和剂量的指导方针.
- 术后实验室检查,以评估一个月内感染并发症的发生率.
主要成果:
- 对抗生素指示指南的遵守率很高 (90.3%),但对选择指南的遵守率很低 (2.8%).
- 对抗生素剂量指南的遵守率为77.8%,而持续时间的遵守率仅为3.4%.
- 在完成随访的患者中 (41.8%),4.6%患有尿路感染,0.7%患有腹感染.
结论:
- 在内分泌学程序中遵守SAP指南显著不理想,特别是关于抗生素持续时间.
- 在指南实施中的偏差需要有针对性的干预来优化SAP.
- 改善SAP实践对于减少传染性并发症和改善患者的治疗结果至关重要.
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