全球和中国六种主要类型的消化系统癌症的负担
Yueyang Zhou1, Kai Song2, Yuqing Chen1
1Center for Prevention and Early Intervention, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Chinese medical journal
|July 3, 2024
概括
消化系统癌症对全球健康构成重大挑战,其中结肠直肠癌是最常见的. 持续的预防工作至关重要,以减少这些广泛的胃肠道癌症的发病率和死亡率.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 消化系统癌症是全球巨大的癌症负担.
- 癌症发病率和死亡率在不同地区和不同人群之间有很大差异.
- 最近的GLOBOCAN 2022数据提供了癌症负担的最新估计.
研究的目的:
- 通过使用GLOBOCAN 2022数据,调查六种主要消化系统癌症的全球和中国特异性负担.
- 分析癌症发病率和死亡率的地理和时间变化.
- 预测中国结肠直肠和肝癌的未来趋势.
主要方法:
- 利用GLOBOCAN 2022数据库,获取食道,胃,结直肠,肝脏,胰腺和胆囊癌的发病率和死亡率数据.
- 根据性别,国家,地区和人类发展指数 (HDI) 分层计算的年龄标准化率.
- 雇员结合点模型和年平均百分比变化 (AAPC) 用于分析中国 (1988-2012) 癌症发病率趋势.
主要成果:
- 在全球范围内,2022年估计有4,905,882例新的消化道癌症病例和3,324,774例死亡.
- 结肠直肠癌的发病率和死亡率在全球是最高的.
- 在消化道癌症负担和一个国家的 HDI 之间观察到正相关性.
- 在中国,食道癌,胃癌和肝癌的发病率下降,而结直肠癌和胰腺癌的发病率从1988年至2012年增加.
- 预计到2050年,结肠直肠癌和肝癌将成为中国的主要癌症类型.
结论:
- 消化系统癌症仍然是全球和中国的主要公共卫生问题.
- 尽管取得了进展,但这些癌症的整体负担仍然存在,需要加强预防策略.
- 第三级预防干预措施对于减轻消化道癌对公共健康的影响至关重要.
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