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负能量平衡会影响围产羊的表现,体形态,体植物结构和胎盘功能

Zhibo Wang¹, Peiyong Chen¹, Yaxu Liang¹

¹Institute of Goats and Sheep Science, Nanjing Agricultural University, Nanjing, China.

Journal of animal physiology and animal nutrition

|July 3, 2024

概括

绵羊的负能量平衡 (NEB) 显著降低了生长性能,改变了血清生物化学,肠发酵和肠细菌. NEB还影响了胎盘功能和基因表达,影响了生殖结果.

科学领域:

动物科学动物科学
生殖生物学生殖生物学
营养生理学营养生理学

背景情况:

围产期内负能量平衡 (NEB) 可以显著影响母羊的生产力和羔羊的发育.
了解NEB效应背后的生理和分子机制对于优化母羊的营养和繁殖成功至关重要.

研究的目的:

调查NEB对围产羊的生长表现,血清生物化学,乳头功能,乳头微生物群和胎盘发育的综合影响.
确定与NEB相关的关键基因和微生物变化及其对生殖表现的影响.

主要方法:

在怀孕130天的20只母羊被分配到正能量平衡 (PEB) 或NEB (70%的料摄入量) 组.
评估了生长参数,血清生化标志物,乳头发酵,乳头细菌组成 (16S rRNA测序),以及乳头乳头和胎盘中的基因表达.
羊羔的出生和断奶体重被记录下来.

主要成果:

NEB显著降低了体重,尸体重量和羔羊出生/断奶重量 (P<0.05).
改变了血清特征 (增加了NEFA,β-基酸盐;降低了胆固醇,白蛋白),减少了乳头发酵 (酸,黄油酸) 和减少了乳头乳头长度.
肠细菌多样性和组成的显著变化,以及与胎盘功能 (运输,增殖,亡,血管生成) 相关的基因的改变表达.

结论:

NEB对绵羊的生长,新陈代谢,功能和动物微生物组合产生负面影响.
NEB影响胎盘基因表达,可能会损害生殖能力.
营养介导的生殖性能调节涉及肠微生物群和胎盘功能之间的复杂相互作用.

关键词:

胡羊胡羊胡羊是什么意思负能量平衡负能量平衡.胎盘功能胎盘功能排骨功能排骨功能转体中的微生物群.

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