在患有肺狭窄症患者的肺置换后,右心功能差异与法洛特四重症相比,肺狭窄症患者的右心功能差异
Alexander C Egbe1, C Charles Jain1, Omar Abozied1
1Department of Cardiovascular Medicine Mayo Clinic Rochester Rochester MN USA.
Journal of the American Heart Association
|July 3, 2024
概括
延迟肺置换 (PVR) 在患有肺狭窄 (PS) 和吐的患者中可能是适当的,因为早期与晚期PVR在右心逆向重塑中没有差异. 这与Fallot患者的四重学相反,在这些患者中,晚期PVR与较少的逆转重塑有关.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 有限的数据存在于肺置换 (PVR) 时间对右心逆转重塑在患者肺吐 (PR) 后干预隔离肺狭窄症 (PS) 的影响.
- 这项研究调查了PS患者的早期与晚期PVR,使用Fallot (TOF) 患者的四分法作为参考组.
研究的目的:
- 为了比较手术后的右心逆转重塑后早期与晚期PVR在患者之前干预PS和PR.
- 评估PVR时间对右心房储应变和右心室自由壁应变的影响.
主要方法:
- 对接受PVR的114名PS患者和291名TOF患者的回顾性分析.
- 在基线,1年和PVR后3年测量右心房水库应变和右心室自由壁应变.
- 早期PVR (共识标准之前) 和晚期PVR (共识标准之后) 之间的改造比较.
主要成果:
- 与TOF组相比,PS组在PVR后1年和3年显示出右心房储应变和右心室自由壁应变的显著改善.
- 在PS组中,在早期和晚期PVR之间没有观察到右心逆转重塑的显著差异.
- 与早期PVR相比,TOF组的晚期PVR与较少的右心逆转重塑有关.
结论:
- 患有缓解PS和PR的患者在右心脏重塑方面表现出更有利的临床过程.
- 在PS患者中延迟PVR可能是临床上适当的策略.
- 在PS与TOF种群中,PVR的时间对右心逆向重塑有不同的影响.
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