相关实验视频
Updated: Apr 29, 2026
An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models
Published on: October 20, 2017
首次在人类中展示高频电动神经阻塞:案例报告
Jayme S Knutson1, Kyle J Chepla, Richard D Wilson
1From the Department of Physical Medicine and Rehabilitation, The MetroHealth System, Cleveland, Ohio (JSK, RDW, MJF, JC, KLK, NB); Department of Orthopedic Surgery, The MetroHealth System, Cleveland, Ohio (KLK); Division of Plastic Surgery, The MetroHealth System, Cleveland, Ohio (KJC); Department of Physical Medicine and Rehabilitation, Case Western Reserve University, Cleveland, Ohio (JSK, RDW, MJF, JC, KLK, NB); Department of Orthopedic Surgery, Case Western Reserve University, Cleveland, Ohio (KLK), Department of Electrical, Computer, and Systems Engineering, Case Western Reserve University, Cleveland, Ohio (MJF); Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio (MJF, SAB, JC, NB); Department of Surgery, Case Western Reserve University, Cleveland, Ohio (KJC); and Research Service, Cleveland Functional Electrical Stimulation Center, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, Ohio (JSK, KJC, RDW, MJF, ECI, JC, KLK).
高频刺激可以阻断肌肉收缩. 这项研究表明,8mA的高频刺激完全阻断了电气诱导的肌肉收缩,为性提供了潜在的治疗方法.
科学领域:
- 神经学 神经学
- 生物医学工程 生物医学工程
背景情况:
- 肌肉是一种使人衰弱的疾病,通常用具有全身副作用的药物治疗.
- 电神经刺激提供了一个潜在的局部治疗方法.
研究的目的:
- 评估使用高频刺激来阻止神经诱导的肌肉收缩的可行性.
- 为了确定发动机块的高频刺激的有效幅度.
主要方法:
- 在前臂肌延长手术期间进行了一项可行性研究.
- 前骨间神经被曝光,并使用神经袖口电极.
- 通过袖子电极进行高频刺激 (20 kHz),以阻断靠近位神经刺激引起的肌肉收缩.
主要成果:
- 通过8mA的峰值至峰值高频刺激,实现了前四角肌肉收缩的完全阻断.
- 在较低的振幅下观察到部分阻塞.
- 肌肉收缩在停止高频刺激后立即恢复.
结论:
- 高频电动神经刺激可以有效地阻断神经诱导的运动活动.
- 这种技术代表了临床应用管理性的重要一步.
更多相关视频
06:36Nerve Stimulator-guided Injection of Autologous Stem Cells Near the Equine Left Recurrent Laryngeal Nerve
Published on: September 26, 2018
11:07In Vivo Intracellular Recording of Type-Identified Rat Spinal Motoneurons During Trans-Spinal Direct Current Stimulation
Published on: May 11, 2020
