斑疹性皮肤炎的全球流行:系统性审查和元分析
Meredith Tyree Polaskey1,2, Christy H Chang3, Karishma Daftary2
1Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, Illinois.
JAMA dermatology
|July 3, 2024
概括
斑疹性皮肤炎影响全球4.38%,患病率因年龄和地区而异. 这一元分析提供了对其全球影响的全面概述.
科学领域:
- 皮肤病学 皮肤病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 斑疹性皮炎是一种常见的慢性炎症性皮肤疾病.
- 它的全球流行,病原和流行病学需要进一步定义.
研究的目的:
- 为了估计血脂性皮肤炎的全球患病率.
- 分析流行病的人口和地理差异.
主要方法:
- 在Embase,PubMed,Scopus和Cochrane数据库中进行了系统的文献搜索.
- 来自121项研究 (1,260,163人) 的数据根据PRISMA指南进行了元分析.
- 随机效应建模用于聚合流行率估计和子组分析.
主要成果:
- 结合起来,血脂性皮肤炎的全球患病率为4.38% (95% CI,3.58%-5.17%).
- 患病率因年龄而异:成人 (5.64%),儿童 (3.70%) 和新生儿 (0.23%).
- 发现了地理差异,南非患病率最高 (8.82%) ,印度患病率最低 (2.62%).
结论:
- 这一元分析提供了一个可靠的估计全球斑疹性皮肤炎的流行率.
- 跨年龄组和地理区域存在显著差异.
- 调查结果强调需要有针对性的公共卫生战略和进一步研究促成因素.
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