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Updated: Jun 22, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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高效的生物合成的rebaudioside M8通过结构指导工程的糖转移酶UGT94E1313的高效生物合成

Lifeng Yang1,2, Mengliang Yang3, Zhiwei Deng3

  • 1Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, P. R. China.

Journal of agricultural and food chemistry
|July 3, 2024
PubMed
概括

研究人员通过提高酶活性和建立级联反应来增强Rebaudioside M8 (Reb M8),一种新型的醇糖化物 (SG) 的产生. 这一突破为食品工业提供了高效的Reb M8合成.

关键词:
UGT94E13 美国人葡萄糖转移酶的使用方法分子动力学模拟模拟蛋白质工程工程 蛋白质工程rebaudioside M8 的使用情况

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Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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