相关实验视频
Updated: Jun 22, 2025
04:36
Author Spotlight: Advancing Intestinal Bacteria Cultivation for Poultry
Published on: May 10, 2024
750
饮食中的Clostridium butyricum和25-氧维生素D3通过肠-大脑轴调节肉的骨代谢
Guangtian Cao1, Yang Yu2, Huixian Wang2
1College of Standardisation, China Jiliang University, Hangzhou 310018, PR China.
Poultry science
|July 3, 2024
概括
用Clostridium butyricum (C.butyricum) 和25-氧维生素D3 (25-OH-D3) 补充肉饮食,改善了生长和骨健康. 这种组合增强了肠-大脑轴调解器,提供了预防腿部疾病和改善肉质的策略.
科学领域:
- 动物科学动物科学
- 营养生物化学 营养生物化学
- 肠道微生物组研究研究
背景情况:
- 肉的腿部疾病造成了重大经济损失,并降低了肉质.
- 需要饮食策略来改善肉骨发育和健康.
研究的目的:
- 评估Clostridium butyricum (C. butyricum) 和25-氧维生素D3 (25-OH-D3) 对肉生长,骨参数和肠道健康的影响.
- 调查这些补充剂对骨发育相关指标和部短链脂肪酸的影响.
主要方法:
- 科布肉被分为四个组:对照组,抗生素组,C.butyricum (Cb) 和C.butyricum + 25-OH-D3 (CbD).
- 评估了生长表现,骨参数,灰 Ca 和 P 含量,骨指标,骨SCFA 和骨元基因组.
- 分析了行为反应 (延迟撒谎) 和肠-大脑轴调解器 (血清素,多巴胺,PYY).
主要成果:
- 补充Cb和CbD显著增加了体重和平均每日增加,同时降低了料与体重的比率.
- 补充剂延长了谎言的延迟时间,改变了骨质卡尔辛,PYY,血清素和多巴胺的水平.
- Cb和CbD增加了的短链脂肪酸,并改变了Alistipes spp.的丰度.
- 受影响的代谢途径包括胰岛素,葡萄糖,PI3K-AKT信号传递,胆酸生物合成和Ca2+运输体.
结论:
- 食C.butyricum和25-OH-D3补充剂对肉生长和骨代谢产生积极影响.
- 结合CbD调节肠-大脑轴介质,这表明了预防腿部疾病和提高 brojlers肉质的潜在策略.
更多相关视频
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
9.3K
06:38In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth
Published on: September 20, 2021
2.4K
相关概念视频
01:25Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
01:17Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
01:23Role of Skin in Vitamin D Synthesis
5.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.1K
01:21Skeleton and Calcium Homeostasis
4.5K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.5K
01:40Bone Remodeling
38.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.3K
01:29Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K