对用于先进药物输送的离子液体和离子凝基生物材料的审查
Muzammil Kuddushi1, Ben Bin Xu2, Naved Malek3
1Department of Chemical and Materials Engineering, University of Alberta, Alberta T6G 1H9, Canada.
Advances in colloid and interface science
|July 3, 2024
概括
离子液体 (ILs) 是用于先进药物输送的多功能材料,增强药物特性并形成像凝一样的新型纳米/微结构. 本综述探讨了用于创新的生物医学应用的IL和基于IL的凝.
科学领域:
- 材料科学 材料科学 材料科学
- 制药科学 制药科学
- 生物医学工程 生物医学工程
背景情况:
- 离子液体 (ILs) 为材料设计提供独特的特性.
- 它们的离子性质提高了药物的溶解性,透性和结合性.
- ILs可以作为绿色溶剂或活性药物成分.
研究的目的:
- 审查ILs在药物配方和输送中的作用.
- 为提供基于IL的凝应用在药物输送中的全面概述.
- 突出IL和基于IL的凝生物医学使用的新视角.
主要方法:
- 在药物配方中对ILs的文献综述.
- 分析ILs作为纳米/微粒子 (小粒,囊泡,凝,乳液) 的结构剂.
- 对基于IL的凝药物递送系统最近的进展进行了审查.
主要成果:
- ILs显著提高了药物的溶解性,透性和结合效率.
- ILs作为各种药物输送载体的有效结构化剂.
- 基于IL的凝在药物输送中显示出有前途的先进应用.
结论:
- 离子液体对于开发新型药物输送系统至关重要.
- 基于IL的凝代表了针对性和有效的药物输送的重大进步.
- 对IL和基于IL的凝的进一步研究可以打开新的生物医学前沿.
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