确保基因组学教育的最佳实践:基因组学教育的范围审查需要评估和评估
Amy Nisselle1, Bronwyn Terrill2, Monika Janinski2
1Australian Genomics Health Alliance, Melbourne, VIC, Australia; Genomics in Society, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, Australia.
American journal of human genetics
|July 3, 2024
概括
有效的基因组学教育对于卫生专业人员实施基因组医学至关重要. 本次审查强调了教育干预和评估的变化,为评估其影响提供了一个新的框架.
科学领域:
- 基因组医学是基因组医学.
- 健康 专业 教育 卫生 专业 教育
- 教育评价教育评价
背景情况:
- 实施基因组医学需要一个有能力的卫生工作人员.
- 在过去的二十年中,为卫生专业人员开发了基因组学教育干预措施.
- 文献中对这些干预措施及其影响的描述有所不同,这阻碍了评估.
研究的目的:
- 为卫生专业人员进行基因组学教育干预措施的需求评估和评估的探索性范围审查.
- 为基因组学教育制定评估框架提供信息.
- 识别和分类用于基因组学教育的评估问题,结果和措施.
主要方法:
- 搜索了对基因组学教育干预措施的需求评估和评估 (2000-2023) 的文献.
- 选了4,659个记录,选择了104篇文章进行纳入.
- 在规划,实施和影响阶段提取,分类和表格化评估数据.
主要成果:
- 包括跨越30多个国家的研究,针对各种各样的卫生专业人员.
- 在评估方法,术语和措施中发现了显著的变化.
- 很少有研究评估了基因组学教育干预的下游,长期结果.
结论:
- 审查发现基因组学教育干预措施的评估存在广泛的变异性.
- 结果为严格,适合目的的基因组学教育评估工具包和框架做出了贡献.
- 这项工作支持基因组医学实施策略中的基因组学教育的证据基础.
相关概念视频
Genomics
36.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.3K
Genome-wide Association Studies-GWAS
13.3K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.3K
Genome Annotation and Assembly
18.8K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.8K
Genome Size and the Evolution of New Genes
2.4K
2.4K
CRISPR and crRNAs
16.9K
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
16.9K
Evolutionary Relationships through Genome Comparisons
5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K


