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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
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功能纳米传感器介导的无线神经调制技术.

Galong Li1, Dongyan Li1, Bin Lan1

  • 1School of Biomedical Engineering, Shaanxi Provincial Key Laboratory of Bioelectromagnetic Detection and Intelligent Perception, Fourth Military Medical University, Xi'an, People's Republic of China.

Physics in medicine and biology
|July 3, 2024
PubMed
概括
此摘要是机器生成的。

功能性纳米材料作为无线神经调节的纳米传感器. 这些材料将外部能量源转化为精确控制神经活动的信号,提供新的治疗可能性.

关键词:
功能性纳米材料的使用离子通道 离子通道通过神经调节进行神经调节.选择了自己的选择.视觉遗传学 视觉遗传学

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科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 神经科学是一个神经科学.

背景情况:

  • 功能性纳米材料提供最小侵入性,高分辨率的无线神经调制.
  • 它们将外部能量 (光,X射线,磁场) 转化为局部热或可见光.
  • 这种激活的目标是光遗传的光素和热敏离子通道,用于精确的神经调节.

研究的目的:

  • 审查用于无线神经调节的关键功能纳米材料的基础知识.
  • 讨论纳米材料设计的最新进展,以改善能量转换.
  • 总结纳米传感器介导神经调节的应用和未来方向.

主要方法:

  • 对上转化纳米粒子,纳米闪电器和磁性纳米粒子的审查.
  • 分析设计策略,以提高能源转换效率.
  • 在神经科学和生理学的实验应用的总结.

主要成果:

  • 功能性纳米材料可以无线控制神经电路.
  • 优化的纳米材料设计增强了能量转化,以实现有效的神经调节.
  • 已证明的应用包括神经元激发/沉默,运动控制和小鼠器官功能调节.

结论:

  • 功能性纳米材料是先进无线神经调节的有希望的纳米传感器.
  • 对纳米材料设计和应用的持续研究对于治疗开发至关重要.
  • 应对当前的挑战将为更广泛的临床翻译铺平道路.