如何在非流行性环境中管理疟疾成年患者
Spinello Antinori1, Andrea Giacomelli1, Giacomo Casalini2
1Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milano, Italy; III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Milano, Italy.
概括
在非流行国家的疟疾诊断,特别是Plasmodium falciparum,往往会延迟,导致可预防的死亡. 本综述提供了有效诊断和向治疗的实际指导,以改善患者的治疗结果.
科学领域:
- 传染性疾病 传染性疾病
- 热带医学 热带医学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 在非流行地区的疟疾诊断和管理面临重大挑战.
- 菌 (Plasmodium falciparum) 是欧洲和北美诊断的最常见的物种,能够引起严重的疾病.
研究的目的:
- 总结在非流行性环境中疟疾的诊断发现和临床特征.
- 为不复杂和严重的疟疾病例提供最新的管理策略.
- 提高意识,并为临床医生提供实用指南.
主要方法:
- 在过去20年的文献搜索.
- 基于世卫组织临床指南和观察研究的建议.
- 在疟疾流行环境中随机研究的推断,如适用.
主要成果:
- 进口疟疾的延迟诊断,特别是P. falciparum,导致可预防的死亡率.
- 涵盖的关键主题包括诊断 (包括分子方法),临床表现和管理.
- 还讨论了抗疟疾药物耐药性模式.
结论:
- 早期和准确的诊断对于在非流行地区有效的疟疾管理至关重要.
- 本综述是临床医生处理进口疟疾的实用指南.
- 基于物种和耐药性模式的向治疗对于最佳的患者护理至关重要.
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