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Updated: Jun 22, 2025

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
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在RNA模板5'端的结构和序列会影响R2逆转移素蛋白对转基因的插入

Sarah M Palm1, Connor A Horton1, Xiaozhu Zhang1

  • 1Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.

RNA (New York, N.Y.)
|July 3, 2024
PubMed
概括

精确的RNA介导转基因插入 (PRINT) 使用R2逆转移子蛋白质将基因插入到核糖核糖核糖核酸基因中. 优化RNA模板的5' ribozyme折叠可以提高基因插入的效率.

关键词:
类似于高强度病毒的 ribozyme.在R2反向转移子中.基因组工程是基因组工程.对于非LTR的反向转移,转基因是指转基因的人类.

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