相关实验视频

Updated: Jun 22, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

长期有效性和XEN45的安全性在开角青光眼患者

Roberto G Carassa¹, Gabriele Corsini^2,3, Giacinto Triolo^2,4

¹Centro Italiano Glaucoma, Viale Tunisia, 45, 20124, Milan, MI, Italy. carassa@glaucoma.it.

International ophthalmology

|July 3, 2024

概括

XEN45植入物,单独或与发泡化,有效降低眼内压力 (IOP) 和减少药物需求在开角青光眼患者,证明了有利的安全性.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
医疗器械医疗器械

背景情况:

开放角光眼 (OAG) 需要有效的长期眼内压力 (IOP) 管理.
植入XEN45是一种最小侵入性的选择,用于降低IOP.
在OAG中评估XEN45植入物的有效性和安全性至关重要.

研究的目的:

在OAG患者中评估XEN45植入物的长期有效性.
为了评估XEN45植入物的安全性,单独或与化混合.
为了确定XEN45植入物对药物使用的影响.

主要方法:

对158个OAG眼睛进行XEN45植入的回顾性单中心研究 (2017年2月 - 2021年12月).
主要终点:与手术前值相比,IOP的平均减值.
手术成功的定义是≥20%的内血压降低和内血压在6-13mmHg之间,有或没有药物.

主要成果:

平均手术前内血压显著减少,从19.4±6.5 mmHg降至12.4±5.0 mmHg (p<0.0001).
平均药物使用量从3.4±0.9下降到0.9±1.3 (p<0.0001).
53.2%的眼睛取得了手术成功,其中58.3%的眼睛完全成功;0.6%的眼睛经历了内眼炎.

结论:

XEN45植入物,单独或与发泡乳化,显著降低OAG患者的内脏压力.
XEN45植入物减少了对眼部潜在药物的需要.
植入XEN45显示了长期OAG管理的良好的安全性.

关键词:

眼内压力眼内压力在MIFS中,MIFS是MIFS,MIFS是MIFS.这就是MIGS.眼睛的低血压药物治疗.视角开放的玻璃眼 (Open-angle glaucoma) 是一种视角开放的玻璃眼.这种XEN植入物是XEN植入物.

更多相关视频

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

相关概念视频

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...