饮食炎症指数可能会增加患有慢性脏病的患者的肉症的风险
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Updated: Jun 22, 2025

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Fatemeh Mansouri1, Fatemeh Jafari2, Sara Ranjbar3
1Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
较高的饮食炎症指数 (DII) 与慢性脏病 (CKD) 患者的肉症风险增加有关. 促炎性食物可能会对这一群体的肌肉健康产生负面影响.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 营养科学 营养科学
- 老年学是指老年学的学科.
背景情况:
- 饮食模式显著影响慢性病 (CKD) 的进展和结果.
- 通过像食炎症指数 (DII) 这样的综合指数来评估饮食,可以全面了解炎症潜力.
- 蛋白质能量浪费 (PEW) 和肉是CKD患者常见的并发症,影响发病率和死亡率.
研究的目的:
- 调查饮食炎症指数 (DII) 与CKD患者中蛋白质能量浪费 (PEW) 和肉症的风险之间的关联.
- 在CKD队列中探索饮食炎症负荷和肌肉健康恶化之间的关系.
主要方法:
- 一项涉及109名来自伊朗雪拉兹的CKD患者的横截面研究.
- 评估饮食摄入量使用经过验证的168项食物频率调查问卷.
- 根据亚洲 sarcopenia工作组 (awgs) 的指导方针诊断出 Sarcopenia;根据国际脏营养和新陈代谢学会 (ISRNM) 的标准诊断出 PEW.
- 用于确定关联的物流回归分析.
主要成果:
- 在较低和较高的DII组之间,和脂肪酸,反式脂肪酸,氨酸,β-胡卜素和维生素C摄入量的显著差异.
- 较高的DII与单变体 (OR=1.379) 和多变体 (OR=1.379) 模型中,无论年龄如何,都显著增加了肉类的几率.
- 年龄也独立地与增加的肉类的几率有关 (OR=1.063).
结论:
- 这项研究表明,促炎性食物在加剧肌肉健康下降,特别是肉,在CKD患者的潜在作用.
- 研究结果强调了饮食质量及其在治疗CKD并发症中的炎症潜力的重要性.
- 建议进行进一步的纵向研究,以确定饮食炎症指数和CKD中的肉症之间的因果关系.
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