空鼻综合征的手术和再生治疗选择:系统性审查
Do Hyun Kim1, Mohammed Abdullah Basurrah2, Soo Whan Kim1
1Department of Otolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Clinical and experimental otorhinolaryngology
|July 4, 2024
概括
手术和再生疗法对空鼻综合征 (ENS) 的症状如鼻塞和干燥有希望. 需要进一步的研究,以建立针对这种具有挑战性的条件的标准化协议.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 再生医学是一种再生医学.
- 手术创新 在外科创新.
背景情况:
- 空鼻综合征 (ENS) 呈现出矛盾的鼻塞,干燥和窒息,往往对保守的管理没有反应.
- 持续的ENS症状需要探索先进的治疗选择.
- 对于耐火性ENS病例,越来越多地考虑进行外科干预和再生技术.
研究的目的:
- 审查和综合现有的关于空鼻综合征 (ENS) 手术和再生治疗方式的文献.
- 评估各种手术和再生方法在治疗ENS症状方面的疗效和结果.
主要方法:
- 在主要数据库 (PubMed,Embase,Scopus,Cochrane,Google Scholar) 进行了全面的文献搜索,直到2022年12月.
- 包括的研究评估了使用经过验证的患者症状得分 (例如,中鼻结果测试,ENS6项问卷) 和临床检查的治疗结果.
- 分析了28项研究,检查了各种材料和手术场所.
主要成果:
- 使用了各种材料,包括聚乙烯植入物和肋骨软骨,前下侧鼻壁是常见的手术地点.
- 大多数研究报告说,手术干预后临床结果和患者报告的症状有显著改善.
- 虽然一般有效,但一些研究指出,特定的心理指标或糖过境时间没有改善;很少报告不良影响.
结论:
- 手术选择和组织再生技术显示出治疗空鼻综合征 (ENS) 的潜力.
- 进一步进行高质量的研究,包括与较大的队列进行随机对照试验,对于开发ENS标准化治疗方案至关重要.
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