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尼古丁在训练有素的男性中加剧了运动热应变:一项随机,安慰剂控制,双盲研究
Nicole E Moyen1, Matthew J Barnes2, Blake G Perry3
1Eight Sleep Inc., New York, New York, United States.
Journal of applied physiology (Bethesda, Md. : 1985)
|July 4, 2024
概括
尼古丁使用通过减少皮肤血液流动,增加运动员和军事人员的热疲劳风险,加剧了运动热应变. 这项研究强调了需要考虑尼古丁使用在热暴露协议的必要性.
科学领域:
- 运动生理学 运动生理学
- 环境生理学环境生理学
- 人类表现的人类表现.
背景情况:
- 强迫性热应变对处于炎热环境中的个人构成风险.
- 尼古丁对温度调节的生理影响尚未完全理解.
- 了解尼古丁的影响对于运动员和军人等风险人群至关重要.
研究的目的:
- 调查尼古丁是否会加剧运动热应变.
- 为了确定尼古丁是否增加代谢热量产生或减少皮肤血流.
- 为了评估尼古丁在高温运动期间对核心和皮肤温度的影响.
主要方法:
- 10名未经尼古丁培训的男性接受了四次试验 (20°C和30°C) 通过皮肤注射尼古丁或安慰剂.
- 参与者在55%V·o2峰值下骑行60分钟,然后在75%V·o2峰值下进行计时赛.
- 测量包括胃肠道温度,皮肤温度,皮肤血流,代谢热量产生和平均动脉压.
主要成果:
- 尼古丁使用逐渐降低皮肤血流 (P=0.01) 和增加皮肤温度 (P=0.02).
- 更高的环境温度 (30°C与20°C相比) 加剧了这些影响.
- 由于核心温度过高或不良症状,两名参与者未能完成试验,这表明热耗风险增加.
结论:
- 急性尼古丁使用会增加热应变,并增加运动热疲劳的风险.
- 主要的机制是皮肤血流反应变,损害了散热.
- 在涉及强力热应变的研究和协议中,建议对尼古丁使用进行查.
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