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Updated: Jun 22, 2025

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氧化结合蛋白类7缺乏导致ER压力介导的apoptosis在podocytes和蛋白尿

Joanne Duara1,2, Maria Torres1,3, Margaret Gurumani1,3

  • 1Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States.

American journal of physiology. Renal physiology
|July 4, 2024
PubMed
概括

氧化结合蛋白类7 (OSBPL7) 缺乏导致内细胞网膜 (ER) 应激,导致慢性病 (CKD) 中的细胞亡. 这突出了OSBPL7作为球损伤的潜在治疗点.

关键词:
压力ERER压力ERER压力慢性脏疾病 慢性脏疾病球体疾病 球体疾病葡萄细胞 (podocytes) 是一个细胞.蛋白质尿症是一种蛋白质尿症.

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