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非经典Wnt信号通路的激活有效地增强了急性髓性白血病中的HLA-A呈现

YuHan Ma1, JunShuai Yue1, Ling Gao1

  • 1Department of Hematology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu, China.

Frontiers in oncology
|July 4, 2024
PubMed
概括

急性髓性白血病 (AML) 细胞逃避免疫监测. 这项研究确定了AML原始细胞中的克隆异质性,并揭示了激活非经典的Wnt信号通路可以调节HLA-A,增强免疫表现.

关键词:
这就是HLA-A.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.免疫系统的逃脱是免疫逃脱.非经典的 Wnt 信号通道这就是 scRNA-seqq.

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