运动计划对成年人的炎症的影响因阻塞性睡眠呼吸暂停的严重程度而异
Devon A Dobrosielski1, Karla A Kubitz1, Mary F Walter2
1Department of Kinesiology, Towson University, 8000 York Road, Towson, MD 21252 USA.
Sleep and biological rhythms
|July 4, 2024
概括
运动干预可以降低肥胖成人中度至重度阻塞性睡眠呼吸暂停 (OSA) 的阿迪波金 (调节脂肪的激素). 然而,一项为期6周的计划并没有显著改善肥胖成人患有OSA的炎症标志物.
科学领域:
- 运动生理学 运动生理学
- 阻塞性睡眠呼吸暂停 (OSA) 是一种疾病.
- 炎症和新陈代谢健康
背景情况:
- 运动是肥胖个体阻塞性睡眠呼吸暂停 (OSA) 的推治疗方法,已知可以改善慢性炎症.
- 运动对炎症标志物的影响可能根据OSA的严重程度而异.
研究的目的:
- 调查六周运动计划对血液炎症标志物的影响是否在肥胖成年人中与没有轻度OSA和中度至重度OSA之间有所不同.
- 评估运动干预后心肺呼吸能力,身体组成,新陈代谢参数,阿迪波金和炎症标志物的变化.
主要方法:
- 超重的肥胖成年人 (BMI > 27 kg/m2) 接受了多睡眠学,以对OSA的严重程度进行分类 (AHI < 15与AHI ≥ 15).
- 参与者完成了为期6周的综合性运动计划 (每周3天).
- 测量包括心肺健康,DXA评估的身体组成,禁食代谢参数,阿迪波金 (勒,阿迪波涅丁) 和炎症标志物 (CRP,IL-4,IL-8,TNF-α) 干预前后.
主要成果:
- 在中度至重度的OSA组中,运动训练显著降低了总脂肪量,瘦素和脂肪素.
- 在没有减轻的OSA组中,运动训练导致总脂肪量显著减少.
- 在OSA严重程度组之间没有观察到基线特征的显著差异.
结论:
- 一个为期6周的炼计划有效地减少了肥胖成人中度至重度OSA的阿迪波金和脂肪质量.
- 运动干预措施不足以改善肥胖成年人患有OSA的常见炎症标志物,无论严重程度如何.
- 需要进一步的研究来确定最佳的运动持续时间和强度,以改善OSA患者的炎症.
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