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在急性缺血性中风患者中预测神经性下尿路功能障碍的诺米克图:一项回顾性研究

Yingjie Hu^1,2, Fengming Hao^1,2, Lanlan Yu^1,2

¹Department of Nursing, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.

Neurourology and urodynamics

|July 4, 2024

概括

这项研究确定了急性缺血性中风 (AIS) 患者的神经性下尿路功能障碍 (NLUTD) 的关键风险因素. 开发了一种预测名录,以帮助对AIS-NLUTD进行早期风险评估和干预.

科学领域:

神经学神经学
泌尿器科泌尿器科泌尿器科泌尿器科
医疗信息学医疗信息学

背景情况:

神经性下尿路功能障碍 (NLUTD) 是急性缺血性中风 (AIS) 后的一个常见并发症.
在AIS患者中早期识别NLUTD的风险因素对于及时干预和改善患者结果至关重要.
现有的AIS-NLUTD预测工具是有限的.

研究的目的:

在经历过AIS的患者中识别与NLUTD相关的显著风险因素.
开发和内部验证用于评估AIS患者NLUTD风险的预测名录.
为医疗保健专业人员提供一个工具,以促进AIS-NLUTD的早期检测和管理.

主要方法:

在2021年6月至2023年2月期间,对373名AIS患者进行了回顾性研究.
两变量分析和LASSO回归确定了潜在的风险因素,随后进行多变量逻辑回归来构建预测模型.
使用ROC曲线,校准曲线,DCA和CIC来评估名图的性能,并通过引导重新抽样进行内部验证.

主要成果:

在AIS患者中NLUTD的发生率为17.7% (66/373).
对于NLUTD的重要预测因素包括NIHSS得分,肺炎,葡萄糖 (GLU),血红蛋白 (HGB) 和高敏感性C反应蛋白 (hCRP).
开发的预测模型显示出出色的性能 (AUC=0.899) 和强大的临床效用.

结论:

已经成功开发和验证了AIS-NLUTD的强大的预测名录.
该工具使医疗保健提供者能够准确评估AIS患者的NLUTD风险.
使用名图的早期风险分层可以导致及时干预,可能减轻AIS-NLUTD的并发症.

关键词:

急性缺血性中风是急性缺血性中风.在这个过程中,因子因子是指因子因子.神经性下游尿路功能障碍神经性下游尿路功能障碍预测模型是一个预测模型.

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