2022年世界卫生组织分类对PitNETS患者多学科管理的临床影响
Miriam Veleno1,2, Antonella Giampietro1,2, Salvatore Raia1,2
1Pituitary Unit, Department of Internal Medicine, Endocrinology and Diabetes, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy.
Minerva endocrinology
|July 4, 2024
概括
2022年世界卫生组织 (WHO) 的分类将垂体腺瘤重新命名为垂体神经内分泌瘤 (PitNETs). 这一更新增强了瘤分类,并有助于临床管理,尽管仍然需要一个分级系统.
科学领域:
- 内分泌学 在内分泌学.
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 世界卫生组织 (WHO) 的下垂体腺瘤分类已在2022年更新.
- 垂体腺瘤现在被称为垂体神经内分泌瘤 (PitNETs).
- 以前的分类 (例如,2017年) 缺乏全面的分层.
研究的目的:
- 审查2022年世卫组织对PitNETs的分类更新.
- 分析修订后的分类对临床患者管理的影响.
- 为了将2022年分类与之前的2017年版本进行比较.
主要方法:
- 审查2022年世界卫生组织对PitNETs的分类.
- 分析2017年至2022年术语和分类标准的变化.
- 评估血统,细胞类型,激素产生和生物标志物在分类中的作用.
主要成果:
- 2022年分类使用瘤细胞系,类型,激素生产和生物标志物进行全面的组织学分类.
- 修订后的命名法反映了对神经内分泌瘤的更广泛的理解.
- 新方法提供了更好的准确性和潜在的预后价值.
结论:
- 2022年世卫组织分类代表了理解和管理PitNET的重大进步.
- 尽管有所改进,但目前还没有针对PitNET的强大分级或分阶段系统.
- 需要进一步的研究来验证诊断方法和开发分级/分阶段系统.
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