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Updated: Jun 22, 2025

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酵母的核心综合体 COMPASS 和人类混合血统白血病 (MLL),核细胞体的结构,功能和识别

Uhn-Soo Cho1

  • 1Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA. uhnsoo@med.umich.edu.

Sub-cellular biochemistry
|July 4, 2024
PubMed
概括

酵母COMPASS和人类MLL复合物甲基化组织素H3 K4. 辅助子单元通过识别核体和无素来增强这种活动,正如最近的结构研究显示的那样.

关键词:
一个指南针指南针.H2B K120 (酵母中的K123) 单基化核酶体 (H2Bub.NCP)H3 lys4 甲基转移酶在MLL中,我们可以看到MLL.核体内核粒子 (NCP) 是一个核体内核粒子.在 SET 域中设置域名.单粒子电子冷显微镜 (cryo-EM) 是一种技术.在X射线晶体学.

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