在情绪和Go/No-Go任务期间,自下而上的平静调制诱导了taVNS的证据
Lucas Camargo1, Kevin Pacheco-Barrios1,2, Anna Carolyna Gianlorenço1,3
1Spaulding Neuromodulation Center, Center for Clinical Research Learning, Spaulding Rehabilitation Hospital, Harvard Medical School, 1575 Cambridge Street, Boston, MA, United States of America.
Experimental brain research
|July 4, 2024
概括
双边透皮耳道漫神经刺激 (taVNS) 在情绪和认知任务期间对大脑活动产生积极影响. 这种非侵入性技术对调节神经生理过程和改善前额α不对称性有希望.
科学领域:
- 神经科学是一个神经科学.
- 神经调节是一种神经调节.
- 心理生理学 心理生理学
背景情况:
- 双边穿皮耳迷走神经刺激 (taVNS) 是一种非侵入性神经调节技术.
- 它已经显示出治疗神经精神疾病的潜力,如,抑郁,焦虑和慢性疼痛.
研究的目的:
- 研究taVNS在情绪和Go/No-Go任务期间对神经生理过程的影响.
- 为了检查taVNS之后的正面α不对称的变化.
主要方法:
- 一个随机的,双盲的,假的受控试验,涉及44名健康个体.
- 定量EEG (QEEG) 在60分钟taVNS会话 (活跃或虚假) 之前和之后记录.
- 参与者接受了情感任务 (悲伤/快乐的面孔) 和Go/No-Go任务.
主要成果:
- 活跃的taVNS在No-Go条件下显著增加了N2振幅,而不是假的.
- 在悲伤的情绪状态下,治疗后观察到脑电图 (EEG) 功率下降.
- 在情感任务期间,对右前半球的前额α不对称性增加.
结论:
- taVNS可能会诱导从下皮层到皮层区域的自下而上的调制.
- 观察到的事件相关潜力 (ERP) 和α振荡的变化表明皮层下反应得到改善.
- 这些神经生理学效应可能会调解taVNS在神经精神疾病中的临床益处.
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