在患有结肠直肠癌的患者中,瘤是手术后决定性预后因素
Michael Osseis1, Elia Kassouf1, Rhea Akel2
1Department of Digestive Surgery, Hôtel-Dieu de France Hospital, Saint Joseph University, Beirut, Lebanon.
Surgical technology international
|July 4, 2024
概括
这项研究发现,在结肠直肠癌手术后,缩症和短期并发症之间没有显著的联系. 然而,年龄和新出现的手术与术后问题增加有关.
科学领域:
- 在瘤学瘤学.
- 外科胃肠道外科手术
- 老年医学 老年医学
背景情况:
- 结肠直肠癌 (CRC) 手术具有固有的风险,需要进行手术前评估,以预测和减轻并发症.
- 标志着肌肉质量和功能丧失的萨尔科佩尼亚,已与增加的手术并发症率有关.
- 了解肉病对结果的影响对于优化CRC切除后的患者护理至关重要.
研究的目的:
- 在接受结直肠癌切除的患者中,研究术前肉类和短期术后结果之间的关联.
- 为了确定肉类是严重并发症的预测因素,解剖管泄漏,传染性并发症,骨髓,或在CRC手术后腹腔内出血.
主要方法:
- 在2018-2020年间对113名经组织学确认的结直肠癌患者进行了回顾性研究.
- 骨肌肉质量使用手术前CT扫描在L3进行量化测量,根据身高标准化,以计算骨质量指数 (SMI).
- 统计分析包括描述性统计数据和多变量线性回归,以评估90天内肉类和术后结果之间的关系.
主要成果:
- 在113名患者中,有15%的患者被确定为sarcopenic.
- 在萨尔科佩尼亚和严重并发症 (III-IV级) (p=0.675) 之间没有发现统计学上显著的关联.
- 萨尔科佩尼亚与道泄漏,感染性并发症,腹膜或腹腔内出血的增加率无关 (p>0.05).
结论:
- 在接受结直肠癌切除的患者中,术前的肉类并没有与短期的术后并发症显著相关.
- 在这个队列中,sarcopenia似乎不是严重并发症,解剖管泄漏或其他不良事件的可靠预测指标.
- 突发性手术和60岁以上的年龄等因素与术后并发症的发生率更高有关.
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