妊娠期体重增加与乳糖发生延迟之间的关联II:系统性审查和元分析
Zhongyan Cao1, Meiling Huang2, Yun Chen2
1The Third Clinical College of Guangzhou Medical University, The Nursing College of Guangzhou Medical University, Guangzhou, People's Republic of China.
概括
过度的孕期体重增加 (GWG) 与乳腺发育II的延迟和减少纯母乳养率有关. 过度GWG的妇女面临这些哺乳挑战的更高风险.
科学领域:
- 产科和妇科 产科和妇科
- 哺乳期和母乳养研究
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 孕期体重增加 (GWG) 是妊娠结果的一个关键因素.
- GWG与乳糖生成II (DOL II) 的开始之间的关联仍然存在争议.
- 了解这种联系对于支持成功母乳养至关重要.
研究的目的:
- 系统地评估GWG与DOL II的比率之间的关系.
- 评估不同的GWG类别如何影响母乳养的开始和持续时间.
- 为产前和产后护理指南提供基于证据的见解.
主要方法:
- 进行了包括248515名女性在内的16项研究的综合元分析.
- 从10个电子数据库提取到2023年5月的数据.
- 随机效应模型被用来计算DOL II和停止母乳养的合并几率比率.
主要成果:
- 过度的GWG显著增加了DOL II的风险 (OR = 1.28,95% CI: 1.15-1.43).
- 怀孕前超重/肥胖妇女过度GWG和体重不足妇女过度GWG的风险明显更高 (ORs分别为3.01和3.32).
- 过度GWG的妇女在产后一个月内更有可能停止纯母乳养 (OR = 0.82,95% CI:0.80-0.85).
结论:
- 过度的GWG会对乳发性II开始的时间产生负面影响.
- 较高的GWG与更高的绝对母乳养产后停止的可能性有关.
- 对适当的GWG的建议可能是优化母乳养成功的关键.
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