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Updated: Jun 22, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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准循环素依赖激酶2 CDK2:从分子对接和动力学模拟的见解 - 一种系统的计算方法来发现新的癌症治疗方法

Bharath Kumar Chagaleti1, Shantha Kumar B1, Anjana G V1

  • 1Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Chengalpattu District, Kattankulathur, Tamil Nadu 603203, India.

Computational biology and chemistry
|July 4, 2024
PubMed
概括

这项研究确定了针对循环林依赖激酶2 (CDK2) 的新型癌症候选药物. 计算方法选化合物,揭示了有前途的治疗剂,具有有利的稳定性和类似于癌症治疗的药物特性.

关键词:
癌症 癌症 癌症 癌症循环素依赖的激酶酶.分子对接是分子对接.分子动力学分子动力学制药体模型的建模.

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