避免针头:一个质量改进计划,在经过重大妇科癌症手术后,引入阿皮克萨班用于延长血栓预防
Kimberly T Stewart1, Helia Jafari2, Jane Pattillo3
1University of British Columbia, Division of Gynecologic Oncology, Canada; British Columbia Cancer, Gynecologic Oncology Tumor Group, Canada.
Gynecologic oncology
|July 4, 2024
概括
引入阿皮克萨班用于延长的术后血栓预防,显著改善了患者体验,并降低了妇科癌症患者的成本,但没有影响坚持或安全性.
科学领域:
- 妇科瘤学 妇科瘤学
- 药理学 药理学 是一个学科.
- 患者体验 患者体验
背景情况:
- 使用埃诺沙巴林的延长术后血栓预防治疗 (EP) 是妇科癌症手术患者的标准.
- 注射性埃诺沙巴林会对患者的体验产生负面影响,导致疼痛和伤.
- 需要改善患者体验并降低与EP相关的成本.
研究的目的:
- 评估引入口服阿皮克萨班作为EP用埃诺沙巴林的替代品.
- 通过减少50%的疼痛和伤来改善患者体验.
- 将遵守率提高5%并降低自付费用.
主要方法:
- 进行了一项中断时间序列质量改进研究.
- 妇科癌症患者在出院时可以选择阿皮克萨班或埃诺沙巴林.
- 标准化订单,患者教育和多学科团队输入引导实施.
主要成果:
- 84%的患者选择了阿皮克萨班,报告明显减少疼痛,伤,并改善了给药信心 (p < 0.0001).
- 患者坚持治疗的比例仍然很高,为92%.
- 出口成本下降,其中91%的人支付不到125美元,而此前的45%. 没有观察到出血或VTE事件的增加.
结论:
- 阿皮克萨班显著改善了患者报告的质量指标,并减少了EP的财务毒性.
- 阿皮克萨班是一种安全有效的口服替代品,用于治疗延长的术后血栓预防.
- 现在,阿皮克萨班是研究中心对EP的首选抗凝剂.
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