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人类冠状病毒HKU1对TMPRSS2宿主受体的识别

Matthew McCallum1, Young-Jun Park2, Cameron Stewart1

  • 1Department of Biochemistry, University of Washington, Seattle, WA, USA.

Cell
|July 4, 2024
PubMed
概括

人类冠状病毒HKU1使用其尖端 (S) 糖蛋白来结合跨膜蛋白酶2 (TMPRSS2),从而引发感染. 研究人员阐明了这种相互作用,揭示了保存的宿主受体使用和潜在的治疗点.

关键词:
HKU1 其他其他:冠状病毒糖屏蔽免疫逃避中和抗体种类热带性标杆糖蛋白

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