开发和初步验证青少年关节炎疾病活动评分的父和子版本
Roberta Naddei1,2, Francesca Ridella3, Francesca Bovis4
1U.O.C. Reumatologia e Malattie Autoinfiammatorie, IRCCS Istituto Giannina Gaslini Genova, Italy.
Rheumatology (Oxford, England)
|July 4, 2024
概括
新的以父母和儿童为中心的青少年关节炎疾病活动分数 (JADAS) 显示出强烈的有效性. 这些得分可以在家中完成,用于在青少年异常性关节炎 (JIA) 中远程监测症状.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 健康结果 测量 测量
- 临床评估工具 临床评估工具
背景情况:
- 青少年关节炎疾病活动评分 (JADAS) 是评估青少年异常性关节炎 (JIA) 疾病活动的关键指标.
- 现有的JADAS版本依赖于医生评估,可能会限制频繁或远程监测.
- 开发患者和家长报告的版本可以提高JIA管理和患者参与度.
研究的目的:
- 开发JADAS的以父母 (parJADAS) 和儿童 (patJADAS) 为中心的版本.
- 为这些新的JADAS版本的有效性和测量特性提供初步证据.
主要方法:
- 对两个大型跨国JIA数据集进行了验证分析.
- 评估的构造有效性,内部一致性,因子结构,区分有效性,响应性和预测有效性.
- 利用了家长/患者报告的疾病活动,疼痛,关节活动和早晨硬的结果.
主要成果:
- 获得0-40分的parJADAS和patJADAS显示出良好的构造有效性,与现有的JIA措施有很高的相关性.
- 观察到令人满意的内部一致性 (克朗巴赫的α>0.80) 和一个单维结构.
- 这些得分有效地区分了疾病状态,预测了结果,并显示了对变化的合理反应 (SRM = 0.71).
结论:
- parJADAS和patJADAS具有强大的测量特性,可以作为医生评估的有效替代品.
- 通过数字技术定期在家完成,为JIA实现实用远程症状监测和远程医疗.
- 这些工具提供了一种实际的方法来加强JIA疾病活动评估和管理.
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